One-Pot Cajun Chicken Alfredo

Featured in: Simple Comfort Plates

This creamy one-pot meal combines tender chicken breast with al dente orzo pasta simmered in a rich Cajun Alfredo sauce. Aromatic spices like smoked paprika and red pepper flakes build a bold flavor profile, while garlic and onion add depth. Finished with Parmesan and fresh parsley, it delivers comfort and zest in under 30 minutes, perfect for busy nights.

With simple preparation—sautéing chicken, toasting orzo, then simmering with broth and spices—this dish offers a balanced blend of creamy, spicy, and savory tastes. Substitutions like shrimp or Andouille sausage bring versatility, while optional veggies add freshness.

Updated on Sun, 23 Nov 2025 11:29:00 GMT
One-Pot Cajun Chicken Alfredo Orzo, a creamy skillet full of tender chicken and flavorful orzo pasta. Pin it
One-Pot Cajun Chicken Alfredo Orzo, a creamy skillet full of tender chicken and flavorful orzo pasta. | freshymeals.com

A quick and creamy one-pot meal that blends tender chicken, al dente orzo, and a zesty Cajun Alfredo sauce. Perfect for busy weeknights, this dish delivers bold flavors and comforting richness in just 30 minutes.

This meal quickly became a favorite on our weeknight rotation thanks to its ease and delicious taste.

Ingredients

  • Chicken: 1 lb (450 g) chicken breast, diced (substitute with shrimp or Andouille sausage if desired), Salt and black pepper, to taste
  • Spice Blend: 1 tbsp Cajun seasoning (adjust for spice preference), 1 tsp smoked paprika (regular paprika can be used), 1/4 tsp red pepper flakes (optional, for extra heat)
  • Base: 2 tbsp olive oil, 2 tbsp butter, 1 medium onion, chopped (yellow or sweet preferred), 3 cloves garlic, minced
  • Pasta: 1 cup (190 g) orzo pasta (substitute with other small pasta if needed)
  • Sauce: 2 cups (480 ml) low-sodium chicken broth, 1 cup (240 ml) heavy cream (or half and half for a lighter version), 1 cup (90 g) Parmesan cheese, freshly grated
  • Garnish: 1 tbsp fresh parsley, chopped

Instructions

Step 1:
Heat olive oil and butter in a large skillet over medium high heat. Add diced chicken, season with salt and pepper, and sear for 3 4 minutes until golden brown. Remove chicken and set aside.
Step 2:
In the same skillet, add chopped onion and sauté for 2 3 minutes until translucent. Stir in minced garlic and cook for 1 minute until fragrant.
Step 3:
Add orzo pasta to the skillet, stirring to combine. Toast for 1 2 minutes until lightly golden.
Step 4:
Pour in chicken broth and sprinkle in Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 10 12 minutes, stirring occasionally, until orzo is al dente and most of the liquid is absorbed.
Step 5:
Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until the sauce is creamy and smooth.
Step 6:
Return the cooked chicken to the skillet and stir to combine. Heat through for 1 minute. Taste and adjust seasoning as needed.
Step 7:
Garnish with fresh parsley before serving.
This flavorful One-Pot Cajun Chicken Alfredo Orzo features a rich sauce and savory, Cajun-spiced chicken and pasta. Pin it
This flavorful One-Pot Cajun Chicken Alfredo Orzo features a rich sauce and savory, Cajun-spiced chicken and pasta. | freshymeals.com

My family gathers around this dish often, sharing both the meal and stories from their day.

Serving Suggestions

Serve with crusty bread or a fresh green salad for a complete meal.

Variations

Add bell peppers or spinach for extra vegetables and vibrant color.

Wine Pairing

This recipe pairs well with a chilled Sauvignon Blanc or a light lager beer.

Imagine the steaming One-Pot Cajun Chicken Alfredo Orzo: a quick, easy weeknight dinner with vibrant flavors. Pin it
Imagine the steaming One-Pot Cajun Chicken Alfredo Orzo: a quick, easy weeknight dinner with vibrant flavors. | freshymeals.com

This one pot Cajun chicken Alfredo orzo is quick, flavorful, and sure to become a family favorite.

Recipe FAQs

Can I substitute chicken with other proteins?

Yes, shrimp or Andouille sausage work well as alternatives. Adjust cooking times accordingly to ensure proper doneness.

How can I control the spice level?

Modify the amount of Cajun seasoning and red pepper flakes based on your heat preference. Start with less and add gradually.

Is there a lighter version of the sauce?

Using half and half instead of heavy cream and reducing the Parmesan cheese slightly lightens the sauce without sacrificing creaminess.

What is the best way to ensure orzo is cooked perfectly?

Simmer the orzo in the broth with a lid on, stirring occasionally, until al dente and most liquid is absorbed, about 10-12 minutes.

Can I add vegetables to this dish?

Absolutely. Adding bell peppers or spinach during cooking adds color and extra nutrients, enhancing the dish's texture and flavor.

One-Pot Cajun Chicken Alfredo

Creamy orzo with tender chicken and Cajun spices, made quickly in one pot for easy weeknights.

How long to prep
10 min
Time to cook
20 min
Overall time
30 min
Recipe by Freshymeals Lily Carter

Dish category Simple Comfort Plates

Skill level Easy

Cuisine type Cajun

Makes 4 Serving size

Dietary details None specified

What you need

Protein

01 1 lb diced chicken breast
02 Salt to taste
03 Black pepper to taste

Spice Blend

01 1 tbsp Cajun seasoning
02 1 tsp smoked paprika
03 1/4 tsp red pepper flakes (optional)

Base

01 2 tbsp olive oil
02 2 tbsp butter
03 1 medium onion, chopped
04 3 cloves garlic, minced

Pasta

01 1 cup orzo pasta

Sauce

01 2 cups low-sodium chicken broth
02 1 cup heavy cream
03 1 cup freshly grated Parmesan cheese

Garnish

01 1 tbsp fresh parsley, chopped

Steps to follow

Step 01

Sear Chicken: Heat olive oil and butter in a large skillet over medium-high heat. Add diced chicken, season with salt and pepper, and cook for 3–4 minutes until golden brown. Remove chicken and set aside.

Step 02

Sauté Aromatics: In the same skillet, add chopped onion and cook for 2–3 minutes until translucent. Stir in minced garlic and cook an additional minute until fragrant.

Step 03

Toast Orzo: Add orzo pasta to the skillet and stir to coat. Toast for 1–2 minutes until lightly golden.

Step 04

Simmer Pasta: Pour in chicken broth and sprinkle Cajun seasoning, smoked paprika, and red pepper flakes. Stir to combine. Bring to a boil, then reduce heat to low. Cover and simmer for 10–12 minutes, stirring occasionally, until orzo is al dente and most liquid is absorbed.

Step 05

Incorporate Cream and Cheese: Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until sauce is creamy and smooth.

Step 06

Combine and Heat Through: Return cooked chicken to the skillet and stir well. Heat for 1 minute. Adjust seasoning as necessary.

Step 07

Garnish and Serve: Sprinkle chopped fresh parsley over the dish before serving.

Tools you’ll need

  • Large skillet with lid
  • Wooden spoon or spatula
  • Chef's knife
  • Cutting board
  • Measuring cups and spoons
  • Grater for Parmesan cheese

Allergy info

Always check each ingredient for allergens and talk to a professional if unsure.
  • Contains dairy: butter, cream, Parmesan cheese
  • Contains gluten: orzo pasta

Nutrition info (per portion)

Nutrition details are for reference only, not a substitute for health advice.
  • Calories per serving: 560
  • Fat content: 28 g
  • Carbohydrates: 45 g
  • Protein amount: 35 g